Table I. Adherence and trypsin sensitivity of P.falciparum to CD36a.
Parasite clone | Trypsin concentration (µg/ml) |
Soybean trypsin inhibitor | |||
---|---|---|---|---|---|
0 | 1 | 10 | 100 | ||
3D7k+ | 719 ± 81 | 41 ± 15 | 21 ± 22 | 5 ± 5 | 281 ± 71 |
3D7-EMPΔ | 66 ± 23 | ND | ND | ND | ND |
EMPΔ1 | 3 ± 25 | 4 ± 2 | 2 ± 1 | 0.5 ± 1 | 6 ± 4 |
EMPΔ2 | 63 ± 39 | ND | ND | ND | ND |
EMPΔ3 | 115 ± 25 | 35 ± 20 | 5 ± 3 | 3 ± 4 | 129 ± 87 |
aThe results are expressed as infected red blood cells bound per mm2 and show the mean ± SEM assayed in triplicate.