. Author manuscript; available in PMC: 2008 Oct 15.

Published in final edited form as: Bioorg Med Chem. 2007 Jul 25;15(20):6565–6573. doi: 10.1016/j.bmc.2007.07.001

Table 1.

Summary of the DQ2 binding results of dimeric peptides 8–15.

Peptides	Carbon atoms in linker	Putative length (Å)	Binding at pH 5.5 (%)^a	Binding at pH 7.3 (%)^a
9	13	14.3	72.8	52.1
10	18	19.8	70.9	54.6
8	29	31.9	62.0	46.3
11	29	31.9	63.2	53.3
12	32	35.2	69.3	50.7
13	41	45.1	70.2	54.5
14	53	58.3	70.2	51.8
15	89	97.9	67.8	38.6

Measurements were made either at pH 5.5 or at pH 7.3. Recombinant DQ2 (4.7 μM) was mixed with fluorescein-conjugated peptide (0.185 μM) at 37°C for 5 h, and the amount of DQ2 bound peptide was calculated as the percentage (×100%) of total peptide. The results are presented as mean of the two experiments with errors <5% of the numerical values.