Table 5.

Percent mutations in CDRs of Heavy and Kappa chains from CSF B cells

	Heavy Chain			Kappa Chain
	n	%M in CDR	Comparison to HCPB	n	%M in CDR	Comparison to HCPB
HCPB	484	47.0	NA	754	55.0	NA
CIS132	182	52.2	=	124	58.1	=
OND341	452	45.8	=	129	58.9	=
OND758	123	45.5	=	64	59.4	=
M125	891	53.3	^	224	60.7	=
M354	73	46.6	=	2	n.d.	n.d.
M368	643	56.0	^	263	52.9	=
M376	95	51.6	=	37	n.d.	n.d.
M484	164	545.7	=	75	n.d.	n.d.
M522	439	49.2	=	250	64.8	^
M584	650	64.5	^	632	61.1	^
M875	64	37.5	=	7	n.d.	n.d.
AVE MS	3019	54.7	^	1369	60.1	^