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. Author manuscript; available in PMC: 2007 Oct 17.
Published in final edited form as: J Neuroimmunol. 2006 Dec 13;183(1-2):189–199. doi: 10.1016/j.jneuroim.2006.10.020

Table 6.

Replacement:Silent Ratio’s in Heavy and Kappa Chains

Heavy Chain R:S Kappa Chain R:S
CDR FR Targeting to: CDR FR Targeting to:
OND132 3.4 1.4 CDR 3.1 1.3 CDR
OND341 5.4 2.0 CDR 3.1 2.5 =
OND758 3.9 2.0 = 4.1 0.9 CDR
M125 3.6 1.5 CDR 3.6 1.7 CDR
M354 7.3 1.8 CDR n.d. n.d. n.d.
M368 4.3 1.6 CDR 4.9 1.6 CDR
M376 4.8 1.5 CDR n.d. n.d. n.d.
M484 4.6 1.9 CDR n.d. n.d. n.d.
M522 4.2 1.2 CDR 3.4 1.4 CDR
M584 5.4 1.1 CDR 3.7 1.4 CDR
M875 2.2 0.7 CDR n.d. n.d. n.d.
AVE MS 3.6 1.4 CDR 3.8 1.2 CDR