Table 7.

Percent Mutations in RGYW/WRCY motifs of Heavy and Kappa Repertoires from CSF B cells

	Heavy Chain				Kappa Chain
	CDR		FR		CDR		FR
	%M in R/W	Comparison to HCPB	%M in R/W	Comparison to HCPB	%M in R/W	Comparison to HCPB	%M in R/W	Comparison to HCPB
HCPB	60	NA	19	NA	60	NA	49	NA
OND132	58.3	=	28.2	=	59.7	=	38.8	=
OND341	53.9	=	39.2	^	60.7	=	49.0	=
OND758	47.7	=	33.3	=	36.1	=	47.8	=
M125	64.3	=	41.9	^	65.2	=	53.4	=
M354	42.4	∨	14.7	=	n.d.	n.d.	n.d.	n.d.
M368	63.3	=	35.2	^	54.0	=	51.6	=
M376	51.4	=	47.4	^	n.d.	n.d.	n.d.	n.d.
M484	58.2	=	40.0	^	n.d.	n.d.	n.d.	n.d.
M522	62.4	=	45.3	^	53.8	=	30.7	∨
M584	45.4	∨	32.3	^	55.4	=	44.7	=
M875	36.8	∨	31.4	=	n.d.	n.d.	n.d.	n.d.
AVE MS	57.7	=	37.9	^	56.5	=	45.4	=