Table 1.

List of potentially modifiable Tf molecular properties

Rate	Definition	Native Value	Ref.
kFeTf,TfR a	Association rate of holo-Tf for TfR	4 ± 1 × 107 M−1 min−1	[15]
kFeTf,TfR,r a	Dissociation rate of holo-Tf from TfR	1.3 ± 0.5 min−1	[15]
kTf,TfR	Association rate of apo-Tf for TfR	0.0 M−1 min−1	[23]
kTf,TfR,r	Dissociation rate of apo-Tf from TfR	2.6 min−1	[19]
kendo b	Endosomal association rate of Tf for TfR	4.4 ± 0.4 × 107 M−1 min−1	[23]
kendo,r b	Endosomal dissociation rate of Tf from TfR	0.056 ± 0.012 min−1	[23]
kFe,rel	Tf iron release rate	1.0 × 102 min−1	Est.

^aRange reported is the 95% confidence interval.

^bRange reported is the mean and standard deviation.