Table 1.
Basal metabolic parameters of energy balance
| Metabolic parameter | Regular diet |
HFD |
||
|---|---|---|---|---|
| WT (n = 11) | Acc2−/− (n = 10) | WT (n = 10) | Acc2−/− (n = 10) | |
| Body weight, g | 30.5 ± 0.3 | 26.2 ± 0.5* | 34.1 ± 0.4 | 28.2 ± 0.8* |
| Fat mass, g | 2.86 ± 0.27 | 2.24 ± 0.26 | 6.37 ± 0.28 | 4.65 ± 0.37† |
| Lean body mass, g | 22.9 ± 0.3 | 20.0 ± 0.5* | 23.11 ± 0.32 | 19.67 ± 0.47* |
| Total energy expenditure | 19.8 ± 0.4 | 23.5 ± 1.4‡ | 22.8 ± 0.6 | 26.0 ± 0.7‡ |
| Food intake | 23.8 ± 1.7 | 30.9 ± 1.3‡ | 25.5 ± 3.0 | 26.2 ± 2.2 |
| Activity, counts | 67.9 ± 9.7 | 84.1 ± 21.1 | 79.4 ± 5.3 | 75.7 ± 10.0 |
| RQ | 0.925 ± 0.013 | 0.933 ± 0.008 | 0.793 ± 0.007 | 0.798 ± 0.007 |
Total energy expenditure and food intake were measured in kilocalories (1 cal = 4.18 kJ) per hour per kilogram of lean body mass. *, P < 0.001; †, P < 0.01; ‡, P < 0.05 (Acc2−/− vs. WT).