Table 2.
Demographic characteristics of samples of patients and controls
| Group | Sample | Material | Study | Subjects | N | Age | Sex, m/f | Diagnostic |
|---|---|---|---|---|---|---|---|---|
| A | Swiss | Skin fibroblasts ± | [GSH], GCL activity, | Controls | 26 | 36.6 ± 12.4 | 1.2 | DIGS |
| t-BHQ treatment | protein | Patients | 26 | 36.7 ± 11.1 | 3.3 | DSM-IV, DIGS | ||
| B | Swiss | Blood samples | Genotyping | Controls | 48 | 34.3 ± 11.6 | 1.2 | DIGS |
| Patients | 66 | 33.9 ± 10.7 | 2.8 | DSM-IV, DIGS | ||||
| C | Swiss | Skin fibroblasts | Baseline [GSH] | Controls | 39 | 35.7 ± 10.4 | 1.1 | DIGS |
| Patients | 33 | 35.3 ± 13.2 | 2.5 | DSM-IV, DIGS | ||||
| D | Danish | Blood samples | Genotyping | Controls | 331 | 40.2 ± 10.5 | 1.5 | Random selection |
| Patients | 322 | 38.8 ± 12.1 | 1.5 | ICD-10 |
Groups A and C are both part of group B. Age is presented as mean ± SD; sex as the ratio between male and female. DSM-IV, Diagnostic System Manual IV; DIGS, Diagnostic Interview for Genetic Studies; ICD-10, International Classification for Diseases.