. Author manuscript; available in PMC: 2007 Oct 17.

Published in final edited form as: Update Cancer Ther. 2007 Mar;2(1):33–39. doi: 10.1016/j.uct.2007.04.004

Table 2.

Potential mechanisms of chemotherapeutic enhancement of immunotherapy.

Chemotherapeutic agent	Mechanism of enhancement
Fluorouracil	Changes tumor phenotype.²⁰
Cyclophosphamide	Decreases negative immunoregulatory cells.⁴⁶
Doxorubicin	Promotes caspase 3-dependent apoptosis.²⁴