Figure 6.
Pre-steady state kinetics analysis of DNA cleavage by IntCat indicates trans activation by IntCB is due to improved efficiency, not tighter substrate binding. Left, initial rates of product formation were monitored as a function of IntCat concentration in the absence (top) and presence (bottom) of IntCB. Right, concentration-dependence of the initial DNA cleavage rates, in the absence (top) and presence of IntCB (bottom).