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. Author manuscript; available in PMC: 2008 Aug 31.
Published in final edited form as: J Mol Biol. 2007 Jun 9;371(5):1405–1419. doi: 10.1016/j.jmb.2007.06.003

Figure 4.

Figure 4

Energy components (kcal/mol) contributing to the overall free energies of binding for wild type and F56 mutant U1A-RNA systems. VAL, ELE and VDW are the solute valence, electronic and van der Waals energy contributions, respectively; GB-ES and NP are the electrostatic and nonpolar contributions to the solvation free energy, respectively; NMODE is the entropy contribution to the free energy; TOTAL is the overall free energy from the summation of the energy components. (a) Absolute energies for wild type, F56A, F56L and F56W systems. (b) Relative energies of F56 mutants compared to wild type. (c) Electrostatic and nonelectrostatic energy contributions of F56 mutants compared to wild type scaled according to Equation 10.