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. 2007 Sep 7;4:17. doi: 10.1186/1476-9255-4-17

Figure 2.

Figure 2

Tumor-necrosis-α expression in myocardial tissue. Representative cross-sections of the myocardium showing immunohistochemical staining for TNF-α in mice administered: 0 LPS (placebo pellets) with either (A) 0 IF, (B) low IF (126 mg IF/kg diet), or (C) high IF (504 mg IF/kg diet); or LPS (pellets releasing 1.33 μg/d) with either (D) 0 IF, (E) low IF (126 mg IF/kg diet), or (F) high IF (504 mg IF/kg diet). Micrographs (20x) show no endothelial expression of TNF-α in the placebo mice but a marked increase in the animals receiving LPS (note arrows indicating TNF-α expression). TNF-α expression was down-regulated with increasing dose of IF.