FIG. 2.
Kinetic models applied: non-compartmental model, two-parameter compartmental model (one tissue compartment), three-parameter compartmental model (one tissue compartment plus vascular pool), four-parameter compartmental model (two tissue compartments), and five-parameter compartmental model (two tissue compartments plus vascular pool). BV, Regional cerebral blood volume, k1…k4, compartmental rate constants, fmax … fT = parameters of the impulse response function. The shaded area represents the model components that are in the field of view of the positron emission tomography (PET) scanner. The presence of vascular blood pool is indicated by partial inclusion in the field of view of the PET scanner.