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. 2007 Oct;177(2):1011–1022. doi: 10.1534/genetics.107.073759

TABLE 1.

Results from the transcriptome scan

Gene product GenBank accession no. h2 QST P-value h2 P-value Inline graphic Fold difference F neutrality test Functional information
Transmembrane protein 14C CA042090 0.14 0.11 3.8 × 10−2 1.0 × 10−2 1.21 18.94* Unknown function
Selenoprotein P, 1b CB509685 0.21 0.11 4.8 × 10−2 8.0 × 10−3 1.31 12.28* Oxidant defense, thyroid hormone metabolism, defense against viral infections
Nucleolar RNA helicase II CB505664 0.32 0.08 2.0 × 10−2 0 1.46 6.03* Ribosomal RNA processing, transcription regulation
Pterin-4-α- carbinolamine dehydratase CB497855 0.44 0.07 8.0 × 10−3 2.0 × 10−3 1.19 3.80 (NS) Tetrahydrobiopterin recycling and biosynthesis, HNF-1-α regulation
Lysozyme type II CA037907 0.28 0.07 2.6 × 10−2 1.8 × 10−2 1.29 5.76* Bacteriolytic function
Tartrate-resistant acid phosphatase type 5 CA045149 0.37 0.07 1.2 × 10−2 2.0 × 10−3 1.39 4.22* Cytochemical marker of macrophages, osteoclasts, and dendritic cells; unknown biological function
Unknown CB496434 0.22 0.19 3.8 × 10−2 0 1.40 22.40*
Unknown CA060749 0.23 0.16 5.0 × 10−2 0 1.31 17.34*
Unknown CB514770 0.38 0.14 1.0 × 10−2 0 1.18 9.30*
Unknown CB514561 0.27 0.13 2.4 × 10−2 0 1.25 12.39*
Unknown CB513854 0.20 0.13 2.6 × 10−2 6.0 × 10−3 1.16 16.42*
Unknown CA060904 0.21 0.13 4.6 × 10−2 6.0 × 10−3 1.26 15.59*
Unknown CB517440 0.44 0.11 1.8 × 10−2 0 1.35 6.13*
Unknown CA056630 0.23 0.11 3.2 × 10−2 4.0 × 10−3 1.30 11.03*
Unknown CA041889 0.31 0.07 3.2 × 10−2 1.6 × 10−2 1.25 5.18*
Unknown CA056760 0.23 0.10 3.8 × 10−2 6.0 × 10−3 1.37 9.88*

cDNA clones corresponding to the 16 genes for which transcription-level QST estimates were in the upper 1.5% of the QST distribution for 1044 cDNA clones representing genes with significant transcription-level heritability. Corresponding QST and heritability estimates (with their P-values from the permutation test), F-statistic from Lande's neutrality test (asterisks indicate significance at the P < 0.05 threshold), fold difference between subpopulations (upstream/downstream), GenBank accession number, and functional information from the literature are presented.