TABLE 2.
Results from the simulation-based ANOVA
| Gene product | P-value | Fold difference | GenBank accession no. | Functional information |
|---|---|---|---|---|
| Creatine kinase (EC 2.7.3.2) | 9.87 × 10−6 | 1.66 | CK990405 | Energy metabolism |
| Thioredoxin-like protein p19 | 9.87 × 10−6 | 0.70 | CB498161 | Redox regulation, protein refolding, transcription factors regulation |
| α-Globin and β-globin | 8.00 × 10−5 | 1.48 | CA051720 | Oxygen transport |
| Phosphoglycerate mutase 2 (EC 5.4.2.1) | 2.16 × 10−4 | 1.47 | CB497792 | Regulation of glycolysis, cell proliferation |
| Invariant chain INVX | 2.65 × 10−4 | 0.85 | CB503772 | MHC class II-associated invariant chain |
| Invariant chain INVX | 2.91 × 10−4 | 0.87 | CK990275 | MHC class II-associated invariant chain |
| NADH-ubiquinone oxidoreductase chain 2 (EC 1.6.5.3) | 3.27 × 10−4 | 1.34 | CN442556 | Energy metabolism |
| Nuclease-sensitive element-binding protein 1 | 3.28 × 10−4 | 0.82 | CB511419 | Transcription factor |
| Invariant chain S25-7 | 4.16 × 10−4 | 0.86 | CB513162 | MHC class II-associated invariant chain |
| Invariant chain S25-7 | 5.04 × 10−4 | 0.75 | CB502487 | MHC class II-associated invariant chain |
| Nucleolar RNA helicase II | 5.64 × 10−4 | 1.46 | CB505664 | Transcription |
| Acidic mammalian chitinase (EC 3.2.1.14) | 7.32 × 10−4 | 1.44 | CB505509 | Chitin catabolism |
cDNA clones representing genes with significant (P < 0.0001) differences in transcription level between the upstream and downstream subpopulations are presented. The corresponding gene identities, P-values, average fold difference (upstream/downstream), and GenBank accessions are provided for each significant cDNA clone, along with brief functional annotations from the literature.