TABLE 5.

McDonald–Kreitman test results for the dm locus

	D. melanogaster		D. simulans
	Synonymous	Nonsynonymous	Synonymous	Nonsynonymous
Total locus
Total divergence
Polymorphism	21	2	15	11
Divergence	49	37	49	37
	P-value = 0.002		P-value = 0.948
Lineage-specific divergence
Polymorphism	21	2	15	11
Divergence	29a	12	10a	19
	P-value = 0.056		P-value = 0.084
Exon 1
Lineage-specific divergence
Polymorphism	7	2	4	7
Divergence	5	5	2	10
	P-value = 0.210		P-value = 0.283
Exon 2 (small sample, n = 12)
Lineage-specific divergence
Polymorphism	14	0	11	4
Divergence	24a	7	8a	9
	P-value = 0.053		P-value = 0.131
Exon 2 (large sample, n = 28)
Lineage-specific divergence
Polymorphism	47	19	11	4
Divergence	9a	4	2a	6
	P-value = 0.886		P-value = 0.026

^aComparisons for which there is a significant relative rates test (Tajima 1993) between the two species.