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. 2007 Oct 16;4(5):249–263. doi: 10.7150/ijms.4.249

Table 3.

Prediction of coronary stenosis by logistic regression with risk factors (“RF”), by logistic regression with risk factors and MI history (“RF + MI”), by logistic regression with risk factors and severity score (cut-off 4.0; “SC + RF”), by logistic regression with risk factors and MI history and severity score (cut-off 4.0; “SC + RF + MI”), and by severity score (cut-off 4.0; “SC”) alone for total population, gender, age groups, and MI history.

n TP TN FP FN a piori Correct Sens Spec PPV NPV LR+ LR- OddsRatio OR 95% CI ROC AUC ROC AUC 95% CI
Lower Upper
Lower Upper
Total RF 423 120 154 68 81 0.475 0.648 0.597 0.694 0.615 0.677 1.949 0.581 3.36 2.25 5.01 0.715 0.667 0.763
RF + MI 423 124 168 54 77 0.475 0.690 0.617 0.757 0.675 0.707 2.536 0.506 5.01 3.30 7.61 0.757 0.712 0.802
SC + RF 423 180 180 42 21 0.475 0.851 0.896 0.811 0.795 0.904 4.733 0.129 36.73 20.92 64.51 0.890 0.857 0.922
SC + RF + MI 423 181 181 41 20 0.475 0.856 0.900 0.815 0.800 0.909 4.876 0.122 39.95 22.53 70.85 0.903 0.874 0.933
SC 423 179 180 42 22 0.475 0.849 0.891 0.811 0.794 0.900 4.707 0.135 34.87 20.00 60.79 0.843 0.802 0.884
Female RF 165 15 100 12 38 0.321 0.697 0.283 0.893 0.371 0.848 2.642 0.803 3.29 1.41 7.67 0.691 0.607 0.776
RF + MI 165 18 106 6 35 0.321 0.752 0.340 0.946 0.587 0.865 6.340 0.698 9.09 3.34 24.69 0.762 0.682 0.841
SC + RF 165 45 100 12 8 0.321 0.879 0.849 0.893 0.640 0.964 7.925 0.169 46.88 17.93 122.58 0.922 0.872 0.972
SC + RF + MI 165 45 103 9 8 0.321 0.897 0.849 0.920 0.703 0.965 10.566 0.164 64.38 23.34 177.59 0.932 0.883 0.981
SC 165 47 98 14 6 0.321 0.879 0.887 0.875 0.614 0.972 7.094 0.129 54.83 19.82 151.70 0.861 0.799 0.923
Male RF 258 111 55 55 37 0.574 0.643 0.750 0.500 0.731 0.525 1.500 0.500 3.00 1.77 5.08 0.687 0.622 0.751
RF + MI 258 104 65 45 44 0.574 0.655 0.703 0.591 0.757 0.523 1.718 0.503 3.41 2.03 5.73 0.728 0.668 0.789
SC + RF 258 136 82 28 12 0.574 0.845 0.919 0.745 0.867 0.835 3.610 0.109 33.19 16.00 68.85 0.864 0.817 0.912
SC + RF + MI 258 137 82 28 11 0.574 0.849 0.926 0.745 0.868 0.847 3.637 0.100 36.47 17.24 77.15 0.884 0.842 0.926
SC 258 132 82 28 16 0.574 0.829 0.892 0.745 0.864 0.792 3.504 0.145 24.16 12.32 47.37 0.825 0.768 0.882
< 65 years RF 246 53 113 30 50 0.419 0.675 0.515 0.790 0.560 0.758 2.453 0.614 3.99 2.29 6.98 0.709 0.645 0.773
RF + MI 246 56 119 24 47 0.419 0.711 0.544 0.832 0.627 0.779 3.239 0.548 5.91 3.29 10.61 0.757 0.697 0.818
SC + RF 246 90 121 22 13 0.419 0.858 0.874 0.846 0.747 0.928 5.680 0.149 38.08 18.21 79.64 0.892 0.849 0.934
SC + RF + MI 246 92 120 23 11 0.419 0.862 0.893 0.839 0.742 0.938 5.553 0.127 43.64 20.24 94.07 0.906 0.866 0.945
SC 246 89 121 22 14 0.419 0.854 0.864 0.846 0.744 0.923 5.617 0.161 34.96 16.95 72.11 0.873 0.826 0.919
> 65 years RF 177 70 50 29 28 0.554 0.678 0.714 0.633 0.750 0.590 1.946 0.451 4.31 2.29 8.12 0.718 0.643 0.793
RF + MI 177 70 54 25 28 0.554 0.701 0.714 0.684 0.776 0.609 2.257 0.418 5.40 2.83 10.30 0.746 0.675 0.818
SC + RF 177 91 60 19 7 0.554 0.853 0.929 0.759 0.856 0.874 3.861 0.094 41.05 16.27 103.62 0.897 0.846 0.949
SC + RF + MI 177 87 61 18 11 0.554 0.836 0.888 0.772 0.857 0.817 3.896 0.145 26.80 11.82 60.76 0.907 0.860 0.953
SC 177 90 59 20 8 0.554 0.842 0.918 0.747 0.848 0.856 3.628 0.109 33.19 13.72 80.27 0.789 0.712 0.865
Female, < 65 years RF 79 0 60 1 18 0.228 0.759 0.000 0.984 0.000 0.919 0.000 1.017 NaN NaN NaN 0.712 0.590 0.835
RF + MI 79 5 61 0 13 0.228 0.835 0.278 1.000 1.000 0.941 NaN 0.722 NaN NaN NaN 0.838 0.739 0.938
SC + RF 79 13 59 2 5 0.228 0.911 0.722 0.967 0.657 0.976 22.028 0.287 76.70 13.38 439.76 0.919 0.849 0.988
SC + RF + MI 79 13 59 2 5 0.228 0.911 0.722 0.967 0.657 0.976 22.028 0.287 76.70 13.38 439.76 0.934 0.876 0.993
SC 79 13 57 4 5 0.228 0.886 0.722 0.934 0.490 0.975 11.014 0.297 37.05 8.72 157.35 0.845 0.730 0.959
Female, > 65 years RF 86 14 42 9 21 0.407 0.651 0.400 0.824 0.516 0.745 2.267 0.729 3.11 1.16 8.35 0.678 0.562 0.794
RF + MI 86 15 46 5 20 0.407 0.709 0.429 0.902 0.673 0.770 4.371 0.634 6.90 2.21 21.58 0.718 0.607 0.830
SC + RF 86 34 42 9 1 0.407 0.884 0.971 0.824 0.722 0.984 5.505 0.035 158.67 19.14 1315.13 0.960 0.925 0.995
SC + RF + MI 86 33 46 5 2 0.407 0.919 0.943 0.902 0.819 0.971 9.617 0.063 151.80 27.74 830.69 0.973 0.944 1.001
SC 86 34 41 10 1 0.407 0.872 0.971 0.804 0.700 0.984 4.954 0.036 139.40 16.98 1144.41 0.834 0.741 0.927
Male, < 65 years RF 167 52 55 27 33 0.509 0.641 0.612 0.671 0.666 0.617 1.858 0.579 3.21 1.70 6.05 0.656 0.573 0.739
RF + MI 167 44 61 21 41 0.509 0.629 0.518 0.744 0.685 0.589 2.021 0.648 3.12 1.62 5.99 0.712 0.635 0.790
SC + RF 167 77 64 18 8 0.509 0.844 0.906 0.780 0.816 0.885 4.127 0.121 34.22 13.96 83.87 0.881 0.827 0.935
SC + RF + MI 167 78 64 18 7 0.509 0.850 0.918 0.780 0.818 0.898 4.180 0.106 39.62 15.58 100.77 0.898 0.850 0.946
SC 167 76 64 18 9 0.509 0.838 0.894 0.780 0.814 0.873 4.073 0.136 30.02 12.62 71.42 0.860 0.799 0.920
Male, > 65 years RF 91 55 8 20 8 0.692 0.692 0.873 0.286 0.861 0.308 1.222 0.444 2.75 0.91 8.31 0.712 0.603 0.821
RF + MI 91 54 7 21 9 0.692 0.670 0.857 0.250 0.853 0.257 1.143 0.571 2.00 0.66 6.06 0.735 0.633 0.837
SC + RF 91 60 17 11 3 0.692 0.846 0.952 0.607 0.925 0.716 2.424 0.078 30.91 7.73 123.54 0.834 0.739 0.929
SC + RF + MI 91 60 17 11 3 0.692 0.846 0.952 0.607 0.925 0.716 2.424 0.078 30.91 7.73 123.54 0.853 0.768 0.938
SC 91 56 18 10 7 0.692 0.813 0.889 0.643 0.926 0.533 2.489 0.173 14.40 4.78 43.36 0.745 0.620 0.869
No MI in history RF 379 86 170 47 76 0.427 0.675 0.531 0.783 0.577 0.750 2.451 0.599 4.09 2.62 6.40 0.719 0.668 0.770
SC + RF 379 142 177 40 20 0.427 0.842 0.877 0.816 0.726 0.922 4.755 0.151 31.42 17.58 56.14 0.881 0.845 0.918
SC 379 142 175 42 20 0.427 0.836 0.877 0.806 0.716 0.921 4.529 0.153 29.58 16.62 52.66 0.834 0.791 0.878

n = number of cases; TP = true positives; TN = true negatives; FP = false positives; FN = false negatives; a priori = a priori probability of stenosis; Correct = fraction of correctly predicted cases; Sens = sensitivity; Spec = specificity; PPV = positive predictive value; NPV = negative predictive value; LR+ = positive likelihood ratio; LR- = negative likelihood ratio; OR = odds ratio; ROC AUC = receiver operating curve area under the curve (for continuous severity score and probabilities from logistic regression models); 95% CI = 95% confidence interval; Lower = Lower boundary of 95% CI; Upper = Upper boundary of 95% CI; NaN = Not a number; MI = Myocardial infarction