Figure 5.

The correspondence of gene and protein structure in the βγ superfamily. Structures of “generic” β- and γ-crystallin genes and of AIM1 are shown with boxes representing exons. Coding sequences are shown in black. Exons are numbered according to the motif(s) they encode; upstream exons in the crystallins have negative numbers, while exons coding for linker peptides in AIM1 are labeled L1 and L2. The phases of introns are shown in parentheses. The fourfold pattern of the greek key motifs in a crystallin is indicated.