Antitumor effect of Mut2 on MethA. On day 7 after tumor inoculation, Mut2 was injected i.v. as indicated by the arrows. Each group consists of 5–10 mice. Dosages represent the amount per injection. □, Control, no drugs; ▴, 0.06 mg/kg; •, 0.23 mg/kg; ▪, 0.94 mg/kg; ○, 3.75 mg/kg. The t test was used. ∗, P < 0.05; ∗∗, P < 0.01; ∗∗∗, P < 0.005. The arrows represent days of Mut2 injection.