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Lack of hypoptensive effect of various doses of Mut2
| Sample | Blood pressure change, %
|
||
|---|---|---|---|
| 1 mg/kg | 3 mg/kg | 10 mg/kg | |
| TNF | −16*** | −7.6* | −10.2** |
| LT | −6.9** | NT | NT |
| Mut2 | −1.8 | −1.5 | 0.9 |
Blood pressure changes 24 hr after cytokines injection are indicated as percentage drop (−) or increase (+) in comparison with the blood pressure of the control animals administered with saline. ∗, P < 0.05; ∗∗, P < 0.01; ∗∗∗, P < 0.001; NT, not tested.
