Figure 4.

Invasiveness and colony formation of Caco-2 cells. (A) Results of the invasion chamber assays quantitating the number of cells that migrate through the Matrigel layer to the filter placed on the bottom of the upper chamber. Cells were counted at a magnification of ×400. (B) Morphology of the colonies formed by control and COX-2-expressing Caco-2 cells. Cells were plated in Matrigel and incubated for 2 weeks prior to photography. (B1) Results for the control Caco-2 cells. (B2) Results for the COX-2-expressing Caco-2 cells. (×200.)