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Comparison of synaptic plasticity in visual cortex of wild-type (solid bars; +/+), homozygous mutant (open bars; −/−), and heterozygous mutant (striped bars; +/−) mice. (A) LTP produced by theta-burst stimulation in 4- to 5-week-old animals. (B) LTD produced by 1 Hz stimulation in 4- to 5-week-old animals. (C) LTP produced by theta-burst stimulation in adult animals.
