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Pros and cons of noninvasive barometric whole-body plethysmography
| pros | cons |
| • minimal restraint of the animal | • enhanced pause as an empirically derived value with unclear physiological relevance |
| • influenced by a number of factors unrelated to bronchoconstriction | |
| • potential to overestimate or underestimate the real degree of airway responsiveness | |
| • data need to be confirmed by invasive methodology |
