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. 2007 Sep 14;8(1):63. doi: 10.1186/1465-9921-8-63

Table 3.

Pros and cons of noninvasive tidal midexpiratory flow measurement

pros cons
• based on physiological principles • underestimation of the magnitude of airway responsiveness as compared with direct measures of pulmonary mechanics
• acceptable agreement with simultaneous invasive measurements of pulmonary mechanics • restraint by neck collar
• physical meaning enables comparability of data from animal to animal
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