Table 2.
List of under-expressed in leiomyomas as compared to scar tissues (keloids/incesional scars)
| Gene Bank | Symbol | Fold Change | Probability | Function |
| AF004709 | MAPK13 | 0.06 | 0.0002 | apoptosis |
| AF010316 | PTGES | 0.09 | 0.0003 | apoptosis |
| NM_014430 | CIDEB | 0.21 | 0.0014 | apoptosis |
| AJ307882 | TRADD | 0.26 | 0.0007 | apoptosis |
| BC041689 | CASP1 | 0.31 | 0.0009 | apoptosis |
| NM_014922 | NALP1 | 0.31 | 0.0025 | apoptosis |
| AF159615 | FRAG1 | 0.33 | 0.0044 | apoptosis |
| BC019307 | BCL2L1 | 0.42 | 0.0027 | apoptosis |
| NM_016426 | GTSE1 | 0.43 | 0.0033 | apoptosis |
| AK027080 | LTBR | 0.50 | 0.0047 | apoptosis |
| M92287 | CCND3 | 0.48 | 0.0028 | cell cycle |
| AJ242501 | MAP7 | 0.2 | 0.0001 | structural molecule |
| AF381029 | LMNA | 0.3 | 0.00001 | structural molecule |
| X83929 | DSC3 | 0.009 | 0.0035 | cell adhesion |
| AB025105 | CDH1 | 0.01 | 0.0009 | cell adhesion |
| AJ246000 | SELL | 0.21 | 0.002 | cell adhesion |
| NM_003568 | ANXA9 | 0.22 | 0.0031 | cell adhesion |
| AF281287 | PECAM1 | 0.36 | 0.0017 | cell adhesion |
| J00124 | KRT14 | 0.0001 | 0.0003 | cytoskeleton/motility |
| BC034535 | KRT6B | 0.005 | 0.0043 | cytoskeleton/motility |
| M19156 | KRT10 | 0.018 | 0.001 | cytoskeleton/motility |
| AJ551176 | SDC1 | 0.039 | 0.0038 | cytoskeleton/motility |
| NM_006478 | GAS2L1 | 0.22 | 0.0016 | cytoskeleton/motility |
| M34225 | KRT8 | 0.26 | 0.0029 | cytoskeleton/motility |
| NM_005886 | KATNB1 | 0.27 | 0.0011 | cytoskeleton/motility |
| AK024835 | CNN2 | 0.47 | 0.003 | cytoskeleton/motility |
| NM_006350 | FST | 0.11 | 0.00001 | extracellular matrix |
| AF177941 | COLSA3 | 0.14 | 0.00001 | extracellular matrix |
| L22548 | COL18A1 | 0.49 | 0.0011 | extracellular matrix |
| M58051 | FGFR3 | 0.007 | 0.0039 | growth factor receptor |
| NM_004887 | CXCL14 | 0.009 | 0.0014 | chemokine |
| AF289090 | BMP7 | 0.13 | 0.002 | cytokine |
| K03222 | TGFA | 0.2 | 0.0048 | growth factor |
| M31682 | INHBB | 0.20 | 0.00001 | cytokine |
| NM_004750 | CRLF1 | 0.26 | 0.0003 | cytokine binding |
| NM_002514 | NOV (CCN3) | 0.28 | 0.0009 | growth factor |
| NM_000685 | AGTR1 | 0.30 | 0.005 | growth factor receptor |
| D16431 | HDGF | 0.42 | 0.0046 | creatine kinase |
| L36719 | MAP2K3 | 0.22 | 0.0048 | protein kinase activity |
| AJ290975 | ITPKC | 0.28 | 0.0036 | protein kinase activity |
| NM_001569 | IRAK1 | 0.33 | 0.0001 | protein kinase activity |
| AB025285 | ERBB2 | 0.45 | 0.0003 | protein kinase |
| AF029082 | SFN | 0.001 | 0.0028 | signal transduction |
| AB065865 | HM74 | 0.04 | 0.0047 | signal transduction |
| AA021034 | LTB4R | 0.06 | 0.0006 | signal transduction |
| NM_004445 | EPHB6 | 0.12 | 0.0038 | signal transduction |
| AF025304 | EPHB2 | 0.17 | 0.0021 | signal transduction |
| AB026663 | MC1R | 0.17 | 0.0046 | signal transduction |
| AF035442 | VAV3 | 0.17 | 0.004 | signal transduction |
| NM_014030 | GIT1 | 0.21 | 0.0025 | signal transduction |
| AB011152 | CENTD1 | 0.21 | 0.0003 | signal transduction |
| AK095244 | CYB561 | 0.23 | 0.0001 | signal transduction |
| AF106858 | GPR56 | 0.23 | 0.0002 | signal transduction |
| AF231024 | CELSR1 | 0.23 | 0.0006 | signal transduction |
| AF234887 | CELSR2 | 0.24 | 0.0003 | signal transduction |
| NM_007197 | FZD10 | 0.25 | 0.0009 | signal transduction |
| NM_014349 | APOL3 | 0.25 | 0.002 | signal transduction |
| NM_004039 | ANXA2 | 0.27 | 0.0044 | signal transduction |
| AI285986 | THBD | 0.29 | 0.0004 | signal transduction |
| M57730 | EFNA1 | 0.31 | 0.0032 | signal transduction |
| NM_002118 | HLA-DMB | 0.33 | 0.0008 | signal transduction |
| AF427491 | TUBB4 | 0.36 | 0.001 | signal transduction |
| NM_005279 | GPR1 | 0.40 | 0.0033 | signal transduction |
| X60592 | TNFRSF5 | 0.40 | 0.0032 | signal transduction |
| BC052968 | EPHB3 | 0.42 | 0.0001 | signal transduction |
| M64749 | CMKOR1 | 0.46 | 0.0014 | signal transduction |
| M21188 | IDE | 0.46 | 0.0031 | signal transduction |
| AB018325 | CENTD2 | 0.47 | 0.0004 | signal transduction |
| AK054968 | ITGB5 | 0.49 | 0.0005 | signal transduction |
| NM_001730 | KLF5 | 0.04 | 0.0021 | transcription factor |
| NM_004350 | RUNX3 | 0.08 | 0.0001 | transcription factor |
| U34070 | CEBPA | 0.11 | 0.0005 | transcription factor |
| AF062649 | PTTG1 | 0.15 | 0.0039 | transcription factor |
| NM_004235 | KLF4 | 0.20 | 0.0005 | transcription factor |
| X52773 | RXRA | 0.20 | 0.0011 | transcription factor |
| AF202118 | HOXD1 | 0.21 | 0.0006 | transcription factor |
| NM_000376 | VDR | 0.21 | 0.0001 | transcription factor |
| NM_006548 | IMP-2 | 0.26 | 0.0031 | transcription factor |
| NM_007315 | STAT1 | 0.32 | 0.00001 | transcription factor |
| NM_004430 | EGR3 | 0.34 | 0.002 | transcription factor |
| NM_003644 | GAS7 | 0.36 | 0.0033 | transcription factor |
| NM_005900 | MADH1 | 0.48 | 0.0028 | transcription factor |
| X14454 | IRF1 | 0.49 | 0.0013 | transcription factor |
| AF067572 | STAT6 | 0.49 | 0.0001 | transcription factor |
| NM_005596 | NFIB | 0.49 | 0.0041 | transcription factor |
| AB002282 | EDF1 | 0.40 | 0.0002 | transcription coactivator |
| AK075393 | CTSB | 0.50 | 0.0016 | protease activity |
| AB021227 | MMP24 | 0.29 | 0.0001 | protease activity |
| AB007774 | CSTA | 0.02 | 0.0018 | cysteine protease inhibitor |
| AF143883 | ALOX12 | 0.06 | 0.0016 | catalytic activity |
| AF440204 | PTGS1 | 0.08 | 0.00001 | catalytic activity |
| NM_000777 | CYP3A5 | 0.14 | 0.0041 | catalytic activity |
| NM_016593 | CYP39A1 | 0.21 | 0.0027 | catalytic activity |
| BC001491 | HMOX1 | 0.23 | 0.0028 | catalytic activity |
| BC020734 | PGDS | 0.26 | 0.00001 | catalytic activity |
| AL133324 | GSS | 0.39 | 0.002 | catalytic activity |
| AF055027 | CARM1 | 0.41 | 0.00001 | catalytic activity |
| NM_001630 | ANXA8 | 0.01 | 0.0006 | calcium ion binding |
| AB011542 | EGFL5 | 0.43 | 0.0001 | calcium ion binding |
| NM_005979 | S100A13 | 0.31 | 0.001 | calcium ion binding |
| NM_020672 | S100A14 | 0.02 | 0.0005 | calcium ion binding |
| NM_005978 | S100A2 | 0.003 | 0.005 | calcium ion binding |
| BC012610 | HF1 | 0.22 | 0.00001 | complement activation |
| AF052692 | GJB3 | 0.03 | 0.0001 | connexon channel activity |
| M12529 | APOE | 0.21 | 0.0001 | metabolism |
| NM_004925 | AQP3 | 0.01 | 0.0003 | transporter activity |
Partial list of differentially expressed genes identified in leiomyomas (African Americans and Caucasians) as compared to keloid/incisional scars as shown in Fig. 1. The genes were selected based on p ranking of p ≤ 0.005 and 2-fold cutoff change selection (F. Change) as described in materials and methods. Table 2 displays the under-expressed genes in leiomyomas as compared to keloid/incisional scars.