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. 2007 Aug 16;8:71. doi: 10.1186/1471-2199-8-71

Table 1.

Nonsense mutations sequenced in the present work

Mutant allele Nucleotide substitution Putative destabilizing motifa

Position/ORF size Codon changeb
his7-1 229/1659 AAA→TAA 311caTTGATtTTaagttgtccaggtTCGATGaTTCa
lys9-A21 605/1341 TTA→TAA ND
trp1-289 403/678 CAG→TAG 436gtTTGATtCagaagcaggtgggacaggtgaactTtTgGATtggaacTCGATtTCTgactgggttggaagg

a The downstream sequences were searched for the presence of DSE (TGYYGATGYYYYY) [15]. The numbers above the sequences indicate the 5' boundaries of putative DSE (underlined sequences) in the corresponding open reading frame (ORF); ND – not detected. b Codon changes in the case of each mutation are shown, nucleotide changes are underlined.