Fig. 7.
The relative abundance of the major in vitro metabolites of 14C-S4 after incubation with different liver enzyme preparations. A, metabolic profile of 14C-S4 in the presence of human, rat, and dog liver S9 fractions. B, metabolic profile of 14C-S4 in the presence of different subcellular fractions of human liver. The reaction was carried out in the presence of different liver enzyme preparations for 2 h at 37°C.