Representative blots showing time-course of stretch-induced changes in ERK (p44/42-T202/Y204), p38-T180/Y182 and JNK-T183/Y185 in cell lysates harvested from NRVM in the absence and presence of AT1 and AT2 receptor blockers (ATB, 10 µM losartan and 10 µM PD123319, respectively). Bar graphs show fold changes in ERK, p38 and JNK phosphorylation after stretch (Str), respectively, when compared to non-stretch (0 min). Values are means ± SEM. N=5 experiments.