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. Author manuscript; available in PMC: 2008 Aug 24.
Published in final edited form as: Cell. 2007 Aug 24;130(4):730–741. doi: 10.1016/j.cell.2007.06.045

Figure 4. Defective retinal electrical activity in response to light in Bmal1−/− mice but not SCN-lesioned wildtype mice.

Figure 4

(A) Electroretinogram (ERG) traces in response to a flash of light for adult wildtype and littermate Bmal1−/− mice under dark- and light-adapted conditions; a- and b-waves labeled on wildtype traces. (B) Quantification of ERG responses in wildtype and Bmal1−/− littermates. Shown are mean and SEM; N = 6 for each genotype. (C) Representative ERG responses of intact wildtype and SCN-lesioned wildtype mice (each N = 5). No significant differences between groups were found for a- or b-wave amplitudes. Mice were C57BL/6, and ERGs were performed between Zeitgeber Time 4 and 9; wildtype and mutant (or intact and SCN-lesioned) mice were studied in alternating order.