Table 1.
Predicted change in the accessible surface area (ASA) due to mutations
| Mutation | Number of residues affected | Mean change in ASA (Å) |
|---|---|---|
| A226T | 6 | +7.1 |
| N228S | 8 | +3.1 |
| G307S | 7 | +5.9 |
| Q526K | 7 | +7.5 |
| D376N | 7 | +11.7 |
| T353M | 7 | −6.8 |
| T262M | 7 | −8.0 |
| I278T | 6 | −4.4 |
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