(a) Raman spectra of RNA duplexes in D- and L-configuration with the sequence [r(CUGGGCGG).r(CCGCCUGG)] at excitation wavelength of the incident photons of 5.2094 eV, 5.0834 eV, and 4.8205 eV. Each spectrum corresponds to the median of three accumulations. (b) Difference spectra at incident photon energies of 5.2094 eV, 5.0834 eV, and 4.8205 eV. The gray dotted background line, which is shown for the difference spectra at 4.8205 eV, demonstrates the size of the experimental error, valid and representative for all three measurements.