Table 4.
Groupa | VEGF | Glut-1 | HK I | HK II | HK III | Ki-67 (%) | TK-1 | Tumor (%) | Necrosis (%) |
---|---|---|---|---|---|---|---|---|---|
FLT | ↔ | ↑ | ↔ | ↑ | ↔ | ↑ | ↔ | ↔ | ↔ |
FDG | ↔ | ↑ | ↔ | ↑ | ↔ | ↑ | ↔ | ↔ | ↔ |
VEGF Vascular endothelial growth factor, Glut-1 glucose transporter protein-1, HK hexokinase, Ki-67 proliferation marker, TK-1 thymidine kinase 1, Tumor (%) percentage of tumor cells, Necrosis (%) percentage of necrosis, ↔ same range as control; ↑ higher than control
aMice from the control, FDG, and FLT group were killed, and all tumors were rapidly excised on days 16, 38, and 36, respectively