Table I.
Steady-state | Crisis | P | |
---|---|---|---|
Haemoglobin (g/l) | 93 ± 2·0 | 83 ± 2·0 | <0·001 |
White blood cell count (109/l) | 8·9 ± 0·5 | 11·9 ± 0·8 | 0·001 |
Platelet count (109/l) | 374 ± 25 | 349 ± 27 | 0·3 |
Absolute reticulocyte count (109/l) | 212 ± 19 | 220 ± 17 | 0·6 |
Lactate dehydrogenase (U/l) | 363 ± 22 | 423 ± 28 | <0·001 |
Aspartate aminotransferase (U/l) | 44 ± 3 | 51 ± 4 | 0·026 |
Alanine aminotransferase (U/l) | 29 ± 2 | 30 ± 2 | 0·8 |
Total bilirubin (µmol/l) | 49·5 ± 5·1 | 58·1 ± 6·8 | 0·09 |
Direct bilirubin (µmol/l) | 6·8 ± 1·7 | 8·5 ± 1·7 | 0·02 |
Alkaline phosphatase (U/l) | 106 ± 9 | 105 ± 8 | 0·9 |
Creatinine (µmol/l) | 61·8 ± 2·6 | 64·5 ± 3·5 | 0·2 |
Data represents mean ± SE.