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Adverse events occurring in ≥ 5% of treated patients (n = 336)
| Event | No. patients (%) |
|---|---|
| Any adverse event | 264 (79) |
| Nausea | 79 (24) |
| Headache | 61 (18) |
| Constipation | 60 (18) |
| Dizziness | 54 (16) |
| Vomiting | 51 (15) |
| Somnolence | 49 (15) |
| Pruritus | 28 (8) |
| Sweating | 22 (6) |
| Insomnia | 20 (6) |
| Dry mouth | 20 (6) |
| Diarrhoea | 19 (6) |
| Fatigue | 18 (5) |
| Peripheral oedema | 17 (5) |
