Table 1.
Statistical Analysis of the Differences in p53, p16, and TERT Expression between Different Stages of Cancer Progression.
| Comparisons | p53 | p16 | TERT | |
| Normal versus hyperplasia | NA versus HA | χ2 = 74.00, P < .001 | χ2 = 53.79, P < .001 | χ2 = 77.00, P < .001 |
| NB versus HB | χ2 = 89.44, P < .001 | χ2 = 71.38, P < .001 | χ2 = 91.38, P < .001 | |
| Hyperplasia versus advanced preneoplasia | HA versus AL | χ2 = 4.63, P = 2.01 | χ2 = 2.10, P = .718 | χ2 = 4.56, P = .041 |
| HB versus DB | χ2 = 39.74, P < .001 | χ2 = 46.93, P < .001 | χ2 = 1.89, P = .169 | |
| Nonneoplastic versus neoplastic lesions | NA versus TUMOR | χ2 = 78.00, P < .001 | χ2 = 57.48, P < .001 | χ2 = 95.00, P < .001 |
| HB versus TUMOR | χ2 = 54.40, P < .001 | χ2 = 40.12, P < .001 | χ2 = 48.64, P < .001 | |
| HA versus TUMOR | χ2 = 11.39, P = .010 | χ2 = 6.32, P = .177 | χ2 = 12.68, P < .001 | |
| HB versus TUMOR | χ2 = 11.34, P = .010 | χ2 = 28.39, P < .001 | χ2 = 18.22, P < .001 | |
| AL versus TUMOR | χ2 = 11.94, P = .008 | χ2 = 2.43, P = .657 | χ2 = 0.67, P = .412 | |
| DB versus TUMOR | χ2 = 17.31, P < .001 | χ2 = 18.16, P < .001 | χ2 = 19.48, P < .001 |
TUMOR, AC and SCC.