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. Author manuscript; available in PMC: 2007 Oct 23.
Published in final edited form as: Curr Neurovasc Res. 2006 May;3(2):107–117. doi: 10.2174/156720206776875830

Fig. (4). mGluRI prevents the expression of Bim.

Fig. (4)

Neuronal protein extracts (50 μg/lane) were immunoblotted with anti-Bim at 6 and 12 hours (h) following with 1 hour pre-treatment with DHPG (750 μM), NO (NOC-9 (shown) or SNP, 300 μM) alone, or combined DHPG (750 μM) with NO. NO led to the rapid expression of Bim at 6 and 12 hours after NO exposure. In contrast, DHPG (750 μM) prevented Bim expression during this same time period. Band density was performed using the public domain NIH Image program (developed at the U.S. National Institutes of Health and available at http://rsb.info.nih.gov/nih-image/) (*P<0.01 vs. control). In all cases, control = untreated neurons.