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. Author manuscript; available in PMC: 2007 Oct 23.
Published in final edited form as: Curr Neurovasc Res. 2006 May;3(2):107–117. doi: 10.2174/156720206776875830

Fig. (5). mGluRI uses Akt1 activation to protect against phosphorylation of β-catenin during NO exposure.

Fig. (5)

Neuronal protein extracts (50 μg/lane) were immunoblotted with anti-phosphorylated-β-catenin (p-β-catenin) at 6 hours following NO (NOC-9 (shown) or SNP, 300 μM) exposure. Transfection with Akt1 siRNA significantly reduced expression of p-β-catenin during DHPG (750 μM) alone or during NO exposure. Band density was performed using the public domain NIH Image program (developed at the U.S. National Institutes of Health and available at http://rsb.info.nih.gov/nih-image/) (*P<0.01 vs. NO).