Table 4.
Multivariate analysis of the effect of participation in harm reduction programmes on HIV and HCV seroconversion.
| HIV | HCV | |||||
|---|---|---|---|---|---|---|
| IRR | 95% CI | P-value | IRR | 95% CI | P-value | |
| Level of harm reduction (definitions described in Table 1) | ||||||
| No harm reduction | 1 | < 0.001 | 1 | < 0.001 | ||
| Incomplete harm reduction | 0.87 | 0.50–1.52 | 1.17 | 0.59–2.31 | ||
| Full harm reduction | 0.43 | 0.21–0.87 | 0.36 | 0.13–1.03 | ||
| Limited dependence on harm reduction | 0.046 | 0.006–0.35 | 0.044 | 0.006–0.35 | ||
| No dependence on harm reduction | 0.20 | 0.078–0.50 | 0.13 | 0.044–0.40 | ||
| Time since start injection drug use (per year) | 0.95 | 0.92–0.98 | < 0.001 | 0.87 | 0.81–0.93 | < 0.001 |
| HIV status of steady partner | ||||||
| No steady partner | 1 | 0.004 | 1 | 0.026 | ||
| HIV-positive steady partner | 4.53 | 2.23–9.21 | 3.49 | 0.84–14.5 | ||
| HIV-negative steady partner | 0.82 | 0.43–1.57 | 0.42 | 0.13–1.37 | ||
| Steady partner with unknown HIV status | 0.75 | 0.18–3.06 | ||||
IRR = incidence rate ratio, 95% CI = 95% confidence interval.