TABLE 1.
Time course of tissue viral titers in i.p.-inoculated 7-8 week old BALB/c mice.
| Days post-viral injection – viral titers (log10 infectious doses/g tissue or mL plasma ± S.D.) | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Virus | Tissue | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 14 | |||
| BaV | Serum | (1/4)a | (1/4) | (1/4) | (3/4) | (1/4) | (0/4) | (2/4) | (2/4) | (1/4) | (1/4) | (1/4) | |||
| NCb | NC | NC | 3.3 ± 0.8 | NC | NC | 3.7 ± 1.6 | 6.1 ± 1.6 | NC | NC | NC | |||||
| BaV | Spleen | (1/4) | (1/4) | (1/4) | (3/3) | (3/4) | (2/4) | (1/4) | (2/4) | (3/4) | (4/4) | (0/4) | |||
| NC | NC | NC | 3.6 ± 0.5 | 4.9 ± 0.6 | 4.3 ± 0.6 | NC | 3.4 ± 0.1 | 3.5 ± 1.2 | 4.0 ± 0.7 | NC | |||||
| BaV | Kidney | (0/4) | (0/4) | (0/4) | (3/4) | (1/4) | (0/4) | (2/4) | (2/4) | (2/4) | (3/4) | (0/4) | |||
| NC | NC | NC | 3.4 ± 0.5 | NC | NC | 2.8 ± 0.7 | 6.6 ± 4.1 | 4.0 ± 1.0 | 3.9 ± 0.8 | NC | |||||
| BaV | Liver | (0/4) | (1/4) | (1/4) | (2/4) | (2/4) | (0/4) | (0/4) | (2/4) | (2/4) | (3/4) | (0/4) | |||
| NC | NC | NC | 2.6 ± 0.0 | 3.2 ± 0.2 | NC | NC | 4.4 ± 2.0 | 3.8 ± 1.4 | 4.6 ± 2.2 | NC | |||||
| BaV | Brain | (0/4) | (0/4) | (0/4) | (1/4) | (2/4) | (2/4) | (1/4) | (4/4) | 4/4 | (4/4) | (1/4) | |||
| NC | NC | NC | NC | 3.6 ± 0.1 | 3.6 ± 1.4 | NC | 8.3 ± 0.8 | 6.7 ± 2.9 | 7.3 ± 2.0 | NC | |||||
|
| |||||||||||||||
| SFV | Serum | (4/4) | (4/4) | (3/4) | (0/4) | (0/4) | (0/4) | (0/4) | (0/4) | (0/4) | - | (0/4) NC | |||
| 4.2 ± 0.2 | 4.7 ± 0.5 | 2.4 ± 0.8 | NC | NC | NC | NC | NC | NC | NC | ||||||
| SFV | Spleen | (4/4) | (4/4) | (4/4) | (4/4) | (2/4) | (1/4) | (0/4) | (0/4) | (0/4) | - | (0/4) | |||
| 3.6 ± 1.8 | 4.8 ± 0.9 | 4.6 ± 0.5 | 3.9 ± 0.7 | 2.5 ± 0.2 | NC | NC | NC | NC | NC | ||||||
| SFV | Kidney | (4/4) | (4/4) | (4/4) | (2/4) | (1/4) | (1/4) | (0/4) | (0/4) | (0/4) | - | (0/4) | |||
| 3.7 ± 2.1 | 4.1 ± 1.0 | 2.7 ± 0.3 | 2.4 ± 0.2 | NC | NC | NC | NC | NC | NC | ||||||
| SFV | Liver | (4/4) | (4/4) | (4/4) | (1/4) | (0/4) | (0/4) | (0/4) | (0/4) | (0/4) | - | (0/4) | |||
| 3.3 ± 2.0 | 4.6 ± 0.8 | 3.4 ± 0.3 | NC | NC | NC | NC | NC | NC | NC | ||||||
| SFV | Brain | (0/4) | (3/4) | (4/4) | (4/4) | (4/4) | (4/4) | (4/4) | (4/4) | (4/4) | - | (0/4) | |||
| NC | 1.7 ± 1.2 | 5.2 ± 0.3 | 6.4 ± 0.9 | 6.9 ± 1.1 | 7.5 ± 0.5 | 6.9 ± 1.4 | 7.3 ± 0.6 | 5.8 ± 1.0 | NC | ||||||
a
Number of samples with detectable virus/total animals assayed.
b
NC- Not Calculated. Means were not calculated when most samples were below the limits of detection.