Figure 2.

Effects of SC19220 and AH6809 on the cAMP responses to PGE₂ by human granulosa–lutein cells. Concentrations of cAMP after a 24-h incubation in the presence of 0–3000 nM PGE₂, either in the absence (circle) or in the presence of 10 μM SC19220 (square) or 10 μM AH6809 (triangle). Values are the mean±s.e.m. for three independent experiments with quadruplicate determinations in each experiment. *P<0·05, **P<0·01 relative to 0 nM PGE₂ in the absence or presence of the PTGER receptor antagonists, as appropriate (one-way ANOVA plus Bonferroni's post hoc multiple comparison test).