A, Images depict dendrites immunocytochemically labeled for PICK1 in neurons treated with and without NO donor (SNAP; 100 μM; 10 min, n = 7). B, Images of similarly treated cells labeled for surface GluR2-AMPARs. (n = 3, Scale bar = 3 μm) C, Quantitation of B and C reveals that NO reduces PICK1 in dendrites while enhancing the surface expression of GluR2 and GluR1 to a lesser extent (* p< 0.05, ***p< 0.001).