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. Author manuscript; available in PMC: 2008 May 24.
Published in final edited form as: Neuron. 2007 May 24;54(4):559–566. doi: 10.1016/j.neuron.2007.05.002

Figure 3.

Figure 3.

Differential requirement of NR2B-signaling for LTP of mature and newborn DGCs in the adult brain. (A) Summary of LTP of EPSPs in GFP+ newborn DGCs at 1 mpi, 2 mpi and in mature DGCs, with or without the addition of ifenprodil (3 µM). EPSPs averaged from 5 consecutive stimuli were taken before and after LTP induction by TBS (arrow) at the time points (1 and 2) indicated in the graphs. Same groups of cells for 1 mpi were used as in Fig. 1A. (B) Summary of the modulation of the mean enhancement of EPSPs (at 45–55 min during recording) by ifenprodil (3 µM) or Ro25-6981 (0.5 µM). Values represent mean ± SEM. The total number of cells examined at each condition is indicated in parentheses (*: p < 0.01; t-test).