Table 1.
Metabolic profile in plasma of the WT and LCAD−/− mice
| Parameter | n | WT | LCAD−/− |
|---|---|---|---|
| Body weight, g | 9 | 26.4 ± 0.8 | 28.0 ± 0.9 |
| Lean body mass, g | 9 | 19.8 ± 0.5 | 20.0 ± 0.6 |
| Whole-body fat content, % body weight | 9 | 8.1 ± 0.5 | 13.1 ± 1.2* |
| Food intake, kcal·kg−1·d−1 | 16 | 611 ± 22 | 547 ± 15* |
| Glucose, mg/dl | 9 | 176 ± 7.3 | 154 ± 26 |
| Insulin, pM | 9 | 98 ± 12 | 103 ± 11 |
| Adiponectin, μg/ml | 10 | 5.9 ± 0.7 | 5.8 ± 0.9 |
| Leptin, ng/ml | 10 | 5.7 ± 1.3 | 10.1 ± 1.7* |
| Resistin, ng/ml | 10 | 5.9 ± 1.9 | 4.3 ± 0.6 |
| IL-6, pg/ml | 10 | 49 ± 27 | 15 ± 5.3 |
| TNFα, pg/ml | 10 | 6.2 ± 0.8 | 6.4 ± 0.7 |
| Fatty acid, mM | 6 | 0.52 ± 0.13 | 0.63 ± 0.08 |
| Triglyceride, mM | 6 | 49 ± 4.4 | 62 ± 6 |
| β-Hydroxybutyrate, mM | 6 | 0.26 ± 0.06 | 0.20 ± 0.03 |
| Total cholesterol, mg/dl | 6 | 73 ± 6.3 | 142 ± 5.9* |
Whole-body fat content was obtained from awake mice with a Bruker Mini-Spec analyzer. Data are presented as mean ± SEM.
*, P < 0.05 compared with WT controls.