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. 2007 Oct 17;104(43):17087–17092. doi: 10.1073/pnas.0704144104

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© 2007 by The National Academy of Sciences of the USA

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Fig. 4. — Effect of HFS of the STN on 5-HT neuronal firing after chronic and acute dopamine depletions. (A) Firing rate of 5-HT neurons before, during, and after STN stimulation (100 Hz, 100 μA) in animals chronically depleted of dopamine by i.c.v. injection of 6-hydroxy-dopamine. (B) Firing rate of 5-HT neurons before, during, and after STN stimulation (100 Hz, 100 μA) in animals acutely depleted of dopamine after coadministration of reserpine and α-methyl-p-tyrosine. *, P < 0.05 versus relevant prestimulus baseline control values.