Fig. 8.

Zip1-GFP containing nuclei showing extensive chromosome movement and nuclear deformations in WT and impaired movement in LatB-treated and ndj1 mutant cells. Video frames captured at the noted intervals with nuclei outlined. (A) WT. Arrows point to deforming nucleus and movement of “maverick” chromosomes out of and then back to the bulk of the chromosomal mass. (B) WT + LatB. WT nucleus treated with LatB where all SC appear virtually immobile. (C) Mutant ndj1 where SCs and nucleus show limited mobility and arrow points to a stationary reference chromosome.