Fig. 2.

Quantitative analysis of aging and treatment effects on dendritic arbor of layer III pyramidal neurons in area 46. Significant age-related dendritic arbor reductions were manifested between young and aged OVX+Veh groups on apical (A and B) and basal (C and D) dendritic length and branch number. An age-related decrease in apical branch number also occurs between young and aged OVX+E groups (B). Young OVX+Veh monkeys demonstrated increased dendritic length and higher branch number when compared with young OVX+E monkeys, although significance was limited to basal dendrites (C and D). Error bars represent SEM.