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. 2007 Jun 25;104(27):11465–11470. doi: 10.1073/pnas.0704757104

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© 2007 by The National Academy of Sciences of the USA

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Fig. 3. — Quantitative analysis of aging and treatment effects on spine density of layer III pyramidal neurons in area 46. Significant treatment effects are seen in both young and aged spine densities in apical (A) (average from 2nd to 4th order) and basal (B) dendrites (P < 0.001 for both young and aged groups). Significant age-related decreases are evident in spine densities on both apical (A) and basal (B) dendrites (P < 0.001 for young and aged OVX+Veh and OVX+E groups). Error bars represent SEM.