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. 1998 May 12;95(10):5562–5567. doi: 10.1073/pnas.95.10.5562

Figure 5.

Figure 5

Western blot analysis of the effects of βAP(1–40) on PKCα immunoreactivity in rat cerebellar granule cells at different days in vitro (DIV) (A) and rat cortical neurons after 3 h of treatment with 100 nM PMA (B). Visual inspection reveals no modifications in PKCα immunoreactivity after βAP(1–40) treatment in rat cerebellar granule cells at 2 days DIV. Decrease of PKCα immunoreactivity is observed after neuronal differentiation at 8 DIV (Left). βAP(1–40) reduces PKCα immunoreactivity in rat cortical neurons at 8 DIV, and treatment of βAP(1–40)-treated cortical neurons with PMA restores the PKCα signal (Right).