Figure 7.

The sensitivity of transfectants to the antiviral and antiproliferative action of IFN. (A) Transfectants were treated overnight with the indicated concentrations of IFNCon1. The cells were then infected with VSV, and the virus yield in the medium was determined by plaque formation. The results of three separate experiments were averaged and expressed as the fold reduction in VSV titer, which was set as 1 in untreated cells. The SEM was <20%. (B) Transfectants were treated with the indicated concentrations of IFNCon1. At day 3, cultures were counted in a Coulter counter. The results of three separate experiments performed in duplicate were averaged. The SEM was <15%.