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. 2007 Aug 30;1(1):e72. doi: 10.1371/journal.pntd.0000072

Table 2. Number of Nodules and Worms Collected and Genotyped After Ivermectin Treatment in 73 Patients Who Provided Pre- and Post-Treatment Nodules.

Rx group No. Nod Female worms Male worms
No. worms (No./Nod.) β-tubulin (%) hsp60 (%) ARP (%) No. Phen. No. worms (No./Nod.) β-tubulin (%) hsp60 (%) ARP (%)
150*1 18 41 (2.28) 32 (78.0) 24 (58.5) 31 (75.6) 39 22 (1.22) 5 (22.7) 10 (45.5) 22 (100.0)
150*4 16 35 (2.19) 21 (60.0) 17 (48.6) 28 (80.0) 34 15 (0.94) 4 (26.7) 5 (33.3) 12 (80.0)
800*1 22 47 (2.14) 27 (57.4) 28 (59.6) 39 (83.0) 45 23 (1.05) 13 (56.5) 10 (43.5) 22 (95.7)
800*4 17 30 (1.76) 18 (60.0) 20 (66.7) 26 (86.7) 29 11 (0.65) 4 (36.4) 4 (36.4) 11 (100.0)
Total 73 153 (2.10) 98 (64.1) 89 (58.2) 124 (81.0) 147 71 (0.97) 26 (36.6) 29 (40.8) 67 (94.4)

Rx group = treatment group (dose μg/kg * frequency per year); No. Nod. = number of nodules; No. worms = number of worms; No./Nod. = number of worms per nodule; β-tubulin = number of worms genotyped for β-tubulin; hsp60 = number of worms genotyped for hsp60; ARP = number of worms genotyped for acidic ribosomal protein; No. Phen. = number of worms phenotyped for fecundity.