Table 2. Number of Nodules and Worms Collected and Genotyped After Ivermectin Treatment in 73 Patients Who Provided Pre- and Post-Treatment Nodules.
Rx group | No. Nod | Female worms | Male worms | |||||||
No. worms (No./Nod.) | β-tubulin (%) | hsp60 (%) | ARP (%) | No. Phen. | No. worms (No./Nod.) | β-tubulin (%) | hsp60 (%) | ARP (%) | ||
150*1 | 18 | 41 (2.28) | 32 (78.0) | 24 (58.5) | 31 (75.6) | 39 | 22 (1.22) | 5 (22.7) | 10 (45.5) | 22 (100.0) |
150*4 | 16 | 35 (2.19) | 21 (60.0) | 17 (48.6) | 28 (80.0) | 34 | 15 (0.94) | 4 (26.7) | 5 (33.3) | 12 (80.0) |
800*1 | 22 | 47 (2.14) | 27 (57.4) | 28 (59.6) | 39 (83.0) | 45 | 23 (1.05) | 13 (56.5) | 10 (43.5) | 22 (95.7) |
800*4 | 17 | 30 (1.76) | 18 (60.0) | 20 (66.7) | 26 (86.7) | 29 | 11 (0.65) | 4 (36.4) | 4 (36.4) | 11 (100.0) |
Total | 73 | 153 (2.10) | 98 (64.1) | 89 (58.2) | 124 (81.0) | 147 | 71 (0.97) | 26 (36.6) | 29 (40.8) | 67 (94.4) |
Rx group = treatment group (dose μg/kg * frequency per year); No. Nod. = number of nodules; No. worms = number of worms; No./Nod. = number of worms per nodule; β-tubulin = number of worms genotyped for β-tubulin; hsp60 = number of worms genotyped for hsp60; ARP = number of worms genotyped for acidic ribosomal protein; No. Phen. = number of worms phenotyped for fecundity.